Sunday, July 26, 2009

-Antibiotics-

What are Antibiotics?

Antibiotics are drugs that either destroy bacteria or prevent their reproduction. Antibiotics that kill bacteria are called "bactericidal" and the ones that stop the growth of bacteria are called "bacteriostatic".


Do you know? That the first natural antibiotics was discovered in 1928 by Alexender Fleming. He actually discovered the penicillin which one of the antibiotics and ever since then scientist have vigorously develop numerous kind of antibiotic pills. Today, over 100 different antibiotics are available. About 90% of antibiotics are made from living organisms such as bacteria, others are produced synthetically, either in whole or in part.

Antibiotics classification:


Although there are several classification schemes for antibiotics, based on bacterial spectrum (broad, narrow) or route of administration (oral, topical), or type of activity (bactericidal, bacteriostatic), the most useful is based on chemical structure. Antibiotics within a structural class will generally have similar patterns of effectiveness, toxicity, and allergic potential.
There are many types of antibiotics namely Penicillins, Fluoroquinolones, Cephalosporins, Macrolides, and Tetracyclines. While each class is composed of multiple drugs, each drug has its unique in some way to destroy the bacteria.


Now, since the first of ever the penicillins, is discovered. So let us explore something new about this first ever born antibiotic:



The structural formula of the Penicillins:


- The penicillinss were effective against many previously serious diseases such as syphilis and Staphylococcus infections. The main disease here, the syphilis is actually sexually transmitted and the penicilins played their importantant as to find against . If this disease left untreated syphilis can damage the heart, aorta, brain, eyes, and bones. Scary Right!!!

There are four types of penicillins:


· The natural pencillins are based on the original penicillin-G structure. Penicillin-G types are effective against gram-positive strains of streptococci, staphylococci, and some gram-negative bacteria such as meningococcus.
· Penicillinase-resistant penicillins are active even in the presence of the bacterial enzyme that inactivates most natural penicillins.
· Extended spectrum penicillins which are effective against a wider range of bacteria.
· Aminopenicillins such as ampicillin and amoxicillin have an extended spectrum of action compared with the natural penicillins.

Penicillins's side effects:



Penicillins are among the least toxic drugs known. The most common side effect of penicillin is diarrhea. Nausea, vomiting, and upset stomach are also common. In rare cases penicillins can cause immediate and delayed allergic reactions - specifically, skin rashes, fever, and anaphylactic shock. Penicillins are classed as category B during pregnancy. So Better To Be Cautious!!!


So overall penicillins do help us and also the doctors to fight against and cure our diseases. BUT do REMEMBER that overdose of antibiotics may also lead us to side effects, which we do not want to suffer it in future…Always do follow the prescribtion of your doctor do not think that consuming lots of antibiotic can help to fight my disease away…Which Is Actually Not!!!

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